CCAM Seminar Series  Speaker: Dr. Ian Wong, Associate Professor of Engineering, Associate Professor of Pathology and Laboratory Medicine, Brown University Title: "Mechanobiology and Topology of Collective Cell Migration"   Abstract: Complex tissue architectures emerge from the interactions of migratory epithelial cells, driving self-organizing and pattern forming behaviors. In particular, transitions between multicellular groups and individuals (i.e. epithelial-mesenchymal transitions) occur widely in embryonic development, wound healing, and cancer progression. Here, I present my group's work on collective cell migration at the interface of mechanobiology and topology. First, I describe our work on orbiting to invasive transitions of multicellular spheroids in 3D matrix, which we have systematically explored using experiment and computational modeling. Second, I present results on topological data analysis for human interpretable machine learning of multicellular patterns. I highlight the use of persistence diagrams and persistence images for dimensionality reduction and classification of tissue architectures. We envision that these physical and mathematical approaches enable new insights into the complexity of tissue morphogenesis in development and disease.   Bio: Ian Wong is Associate Professor of Engineering, and of Pathology / Laboratory Medicine at Brown University. He engineers new miniaturized technologies based on biomaterials and microfluidics to investigate cancer cell invasion, drug resistance, and heterogeneity. He is also interested in the unconventional fabrication of bio and nano materials using self-assembly and 3D printing. He did his graduate work on the directed self-assembly of biomolecular materials with Nick Melosh, receiving a Ph.D. in Materials Science and Engineering from Stanford University. His postdoctoral training was with Mehmet Toner and Daniel Irimia at the Center for Engineering in Medicine at Massachusetts General Hospital. Location: CGSB Grossman Auditorium Via Webex: https://uchc.webex.com/uchc/j.php?MTID=mac08cf7c2a074edebb81c5014fa956e6 (https://uchc.webex.com/uchc/j.php?MTID=mac08cf7c2a074edebb81c5014fa956e6)  Meeting number (access code): 2632 055 2912 Meeting password: CCAMseries Guest Host: Dr. Abhi Deb Roy

For the full class schedule, descriptions, and to register, please visit the UConn Recreation website (https://recreation.uconn.edu/group-fitness-schedule/).

Learning Objectives: Participants will (be able to): 1.Formulate pre-operative balloon sinuplasty evaluation and selection 2.Explain pre-operative balloon sinuplasty patient preparation 3.Describe balloon sinuplasty procedure

The University of Connecticut's Master's of Arts in Research Methods, Measurement, and Evaluation (mailto:https://researchmethodsmasters.online.uconn.edu/) (RMME MA) is a 100%-online, 30 credit-hour program consisting of 6 core courses paired with 4 electives. Offered through the Neag School of Education's Educational Psychology Department, the RMME MA places extensive focus on research methods, techniques, and practices; quantitative data analysis; educational measurement; and program or policy evaluation. The RMME MA program is designed to create versatile practitioners, capable of engaging in multiple fields across disciplines. Applications are accepted on a rolling basis. The RMME Admissions Committee reviews all completed submissions after the application deadline.Please submit application materials (https://researchmethodsmasters.online.uconn.edu/how-to-apply/) no later than June 13 for Fall Semester enrollment.

The importance of evaluating the impact of programs cannot be understated. In fact, program evaluation is a required component for securing all kinds of grants from local, state, and federal agencies. But what if you find yourself needing to learn about the cutting edge evaluation methods and tools? What if you find yourself asked to do an internal evaluation for your organization, with no or limited formal training? What if you need to hire an evaluator, but don't know how or who to select? Where do you start? Right here – at UConn. The evolution of program evaluation and its extensive use in both public and private sectors has given rise to a wealth of quantitative and qualitative evaluation tools. By earning the Program Evaluation Online Graduate Certificate from UConn (https://progeval.uconn.edu/), you'll arm yourself with the skills and knowledge needed to take on the responsibilities of conducting evaluations – or making sure you're an informed consumer capable of commissioning an evaluation from an external source.Please submit application materials (https://progeval.uconn.edu/admissions/) no later than June 13 for Fall Semester enrollment.

Art exhibit highlighting creative the creative talent of UConn Health Employees from across the organization.