The exhibiting artists are Marsha Borden, Helena Chastel, Kathryn Frund, Phoebe Godfrey, Hugh MacDonald, Bob Pavlik, Dan Potter, and R. Douglass Rice. Open Air 2025 is open daily and will remain on view through October 6, 2025. June 19, 2025 iis the last day to visit indoor art exhibitions. Exhibitions inside the AVS Gallery will resume on September 11, 2025

UConn Health Day 2 new employee orientation is conducted on Saba. It focuses on comprehensive training for our newest workforce, covering diversity awareness, sexual harassment prevention, and compliance to ensure a respectful and compliant work environment.AgendaDay 2Format: Saba Self-Guided Learning Time: 8 am - 4:30 pm Location: RemoteActivities: Dive deeper into your compliance and role-specific training and explore resources at your own pace.

Dr. Amy MacQueen Wesleyan University Host: Stacey HanlonZippers and Stitches in the Meiotic Nucleus Dr. MacQueen will present data that informs how we think one meiosis-specific protein, Zip1, manages to carry out two different jobs within the meiotic nucleus. Zip1 carries out two independent activities that each contribute to ensuring chromosomes generate a stable association with their proper (homologous) pairing partners, a task that is critical for the formation of gamete nuclei carrying the proper number of chromosomes. Interestingly, one of Zip1's critical jobs involves processing DNA recombination intermediates at discrete sites along chromosomes, while Zip1's other job involves the assembly of a relatively large chromosomal complex that globally "zips" the entire length of chromosome axes into close proximity. We have acquired data showing that Zip1's two activities are regulated by adjacent regions of its N terminal tip, and that phosphorylation may serve as a molecular "switch", changing Zip1's capacity to carry out these two roles.Publications:Full-Length Synaptonemal Complex Grows Continuously during Meiotic Prophase in Budding Yeast (https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002993)Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein (https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008201)Proximity labeling reveals new functional relationships between meiotic recombination proteins in S. cerevisiaeMacQueen Lab website (https://macqueenlab.research.wesleyan.edu/)

GI Grand Rounds conferences take place weekly on Wednesdays at noon via Webex. Please contact Amy Pallotti to be added to detailed conference announcement emails.